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#115575 - 03/25/16 05:41 PM Re: Journal papers online - reference list [Re: Wieslaw]
Wieslaw Offline
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Classroom Professor

Registered: 09/18/09
Posts: 3751
Loc: Denmark
Terrifying:

Detection and characterization of avian leukosis virus in Marek's disease vaccines.

http://www.ncbi.nlm.nih.gov/pubmed/16863069


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#115576 - 03/26/16 05:46 AM Re: Journal papers online - reference list [Re: Wieslaw]
Robbie Online   content
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Registered: 01/19/15
Posts: 258
Loc: Ontario Canada
That's from 2006, I wonder if it's still an issue?

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#115580 - 03/26/16 06:16 PM Re: Journal papers online - reference list [Re: Robbie]
KazJaps Offline
Classroom Professor

Registered: 08/30/02
Posts: 2792
Loc: Australia
Yes, still an issue.

Peng Zhao, Xuan Dong, and Zhizhong Cui
2014. Isolation, identification, and gp85 characterization of a subgroup A avian leukosis virus from a contaminated live Newcastle Disease virus vaccine, first report in China.
Poultry Science (September 2014) 93 (9): 2168-2174
http://www.ncbi.nlm.nih.gov/pubmed/25002550
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Ever heard of Egg Drop Syndrome in chickens? Apparently the virus came about in chickens from contaminated vaccines (developed using duck embryos):

Merck Vet Manual, EDSV:
Quote:
It is thought that the virus was introduced to chickens through a vaccine that had been grown in contaminated duck-embryo fibroblasts. The virus became established in chickens, causing substantial problems with egg shell quality and loss of eggs.


Edited by KazJaps (03/26/16 06:33 PM)
Edit Reason: added 1st paper link

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#115583 - 03/26/16 07:43 PM Re: Journal papers online - reference list [Re: KazJaps]
Redcap Online   content
Ruler of the Roost

Registered: 08/14/06
Posts: 946
Loc: Germany
Yes, in the german poultry forum there is an user, who made experience with EDS - as far as I know in show breeds. She has a mixed flock of different breeds and don't hatch, so it came into her flock by a purchase. She vaccinates against EDS since then.
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#115584 - 03/26/16 07:45 PM Re: Journal papers online - reference list [Re: KazJaps]
KazJaps Offline
Classroom Professor

Registered: 08/30/02
Posts: 2792
Loc: Australia
I suppose this following paper is somewhat reassuring:

Schat KA, Erb HN. 2014 Lack of evidence that avian oncogenic viruses are infectious for humans: a review. Avian Dis. 2014 Sep;58(3):345-58.
http://www.ncbi.nlm.nih.gov/pubmed/25518427

The paper is mostly about chicken meat processing workers (whether any human risks from avian viruses such as Mareks, Avian Leukosis, REV). It also touches on the history of human vaccine contaminants (from chicken embryo developed vaccines):

Quote:
Moreover, humans vaccinated with exogenous or endogenous ALV-contaminated vaccines against yellow fever, measles, and mumps did not become antibody- or virus-positive for ALV. The risks for human infection with REV are similarly limited......


And about the Marek's virus (MDV)
Quote:

....MDV is typically associated with infection of chickens, and almost all experimental data show that MDV cannot infect mammalian cells or animals, including nonhuman primates. One study reports the presence of MDV gD DNA in human sera, but this finding could not be confirmed by another group.

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#115585 - 03/26/16 08:19 PM Re: Journal papers online - reference list [Re: Redcap]
Redcap Online   content
Ruler of the Roost

Registered: 08/14/06
Posts: 946
Loc: Germany
There are contradictionary results.

Particularly Herpes Viruses should be considered with caution
A few months ago I have found only two studies about this topic (both from 1973) - and with contradictionary claims.



Quote:
These data supported earlier findings and provided additional circumstantial evidence that MDV and HVT do not constitute a public health hazard.

http://jnci.oxfordjournals.org/content/51/4/1123.abstract

Quote:
Common antigenicity has been discovered between glycoprotein antigens obtained from leukotic lesions of chickens with Marek’s disease and antigens obtained from a variety of human cancers. This suggests that Marek’s disease herpesvirus is a possible etiological agent in human cancer.

https://www.karger.com/Article/Pdf/224813

So - if the Marek virus can be considered as possible reason of human cancer it should prick up your ears because in the last 40 years the virulence has multiplied - by the vaccines itself. Nevertheless vaccination is still considered as the best way for food safety:

http://www.pbs.org/newshour/updates/tthis-chicken-vaccine-makes-virus-dangerous
Quote:
“Food chain security and everything rests on vaccines. They are the most successful and cheapest public health interventions that we’ve ever had. We just need to consider the evolutionary consequences of these ones with leaky transmission.”


Who knows why there are so many cancer patients today? Meat consumption per se has been repeatedly discussed, but perhaps it is especially Marek-contaminated meat (under the vaccine coverage)?

This is a newer study, which I could find finally
http://www.microbiologyresearch.org/docs...9E01B63EFB3B2DB
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#115586 - 03/26/16 09:07 PM Re: Journal papers online - reference list [Re: Redcap]
KazJaps Offline
Classroom Professor

Registered: 08/30/02
Posts: 2792
Loc: Australia
At least the Marek's herpes virus is not transmitted vertically through hen eggs (& therefore not a human vaccine contaminant).

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#115587 - 03/26/16 09:34 PM Re: Journal papers online - reference list [Re: Redcap]
Redcap Online   content
Ruler of the Roost

Registered: 08/14/06
Posts: 946
Loc: Germany
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#115592 - 03/27/16 04:54 AM Re: Journal papers online - reference list [Re: Redcap]
Robbie Online   content
Flock Leader

Registered: 01/19/15
Posts: 258
Loc: Ontario Canada
Maybe all those people who are blaming vaccines for all kinds of illness including autism aren't so crazy? It's insane how many vaccines are given to kids these days. Here's the American recommended list:
http://www.cdc.gov/vaccines/schedules/hcp/imz/child-adolescent.html

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#115593 - 03/27/16 09:26 AM Re: Journal papers online - reference list [Re: Robbie]
Redcap Online   content
Ruler of the Roost

Registered: 08/14/06
Posts: 946
Loc: Germany
But there are mainly vaccine adjuvants blamed like Thiomersal, which is ironically no longer used (in children vaccines).
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